A DD in the east med would mean egypt is a no go on G1. Also a big change in favour of the allies.
Not quite. You could still attack with a bomber and your transport with some chance of success, but very risky. Actually, this is the change I would be most happy with. It would also make sense since in all other A&A games UK has had ships in the Mediterranean Sea. It was the naval presence at Alexandria that hindered Rommel from getting supplies and to win that battle of El-Alamein, and this would very much improve the historical feel of the game! Actually, the British had something like 4 cruisers, 1 carrier and 3 battleships at Alexandria in early '41 at the time of the Battle of Cape Matapan and this should translate into something! Link:
http://www.naval-history.net/WW2RN09-194101.htm
If you don’t attack Egypt as Germany on turn 1, you would be forced to attack the UK fleet outside Gibraltar with subs and aircraft to protect the Italian fleet from attack and then you wouldn’t be able to wipe out the British Home Fleet. Another good change. If you survive with the fighter in Egypt, you might also strengthen India’s defenses.
PS. A cruiser at India would also make sense, given that HMS Prince of Wales and HMS Repulse were at Singapore in '41. Then Japan would think twice of attacking with just 2 fighters vs. cruiser and destroyer and if they don’t, those two infantry in Transjordan could ALSO be sent to India. DS.
PPS. Check this table of the Pacific at-start ships, at bottom of this page:
http://www.naval-history.net/WW2RN11-StartPac.htm
Considering the amount of cruisers in the Pacific in '41, UK and US should have one each and Japan two (Italy had 21 cruisers at the start of the war, Japan 40, USA 21, UK 35 and Germany 7). Battleships and carriers seem OK but Japan should have one more destroyer at least. DDS.